Retina ganglion cell electrophysiology In the retina, ganglion cells convey the images processed from photoreceptors, horizontal and amacrine cells to the brain. Many different types of ganglion cells have been identified in vertebrates and humans but their characteristics and physiological functions are still to be defined. By using flat-mounted retina of adult mice as a model, we observe the electrical activity of ganglion cells and we analyse the ionic conductance that contributes to sustain this activity. By recording with the patch-clamp technique and with a multi-electrode-array system, we study ganglion cell electrophysiological properties at the level of the single cell and in the intact retinal networks.
|
